Flow Cytometry in Preclinical Drug Discovery

Flow Cytometry in Preclinical Drug Discovery

by | Jul 18, 2024 | Blog

Flow cytometry is a powerful analytical technique widely used in preclinical drug discovery for its ability to analyze the physical and chemical properties of cells and particles in a fluid as they pass through at least one laser. This technology has revolutionized...
Immune Response and Pain

Immune Response and Pain

by | Jul 10, 2024 | Blog

The relationship between the immune response and pain is complex and multifaceted, involving intricate interactions between the nervous and immune systems. Pain, a critical component of the body’s defense mechanism, signals potential or actual damage to tissues,...
Immunogenicity and Antigenicity

Immunogenicity and Antigenicity

by | Jul 3, 2024 | Blog

Immunogenicity and antigenicity are two fundamental concepts in immunology that, while related, describe different aspects of how the immune system interacts with foreign substances. Understanding these concepts is crucial for fields like vaccine development,...
Immunotoxicity and Immune-Mediated Toxicity

Immunotoxicity and Immune-Mediated Toxicity

by | Jun 26, 2024 | Blog

Immunotoxicity and immune-mediated toxicity are two critical concepts in toxicology and immunology that describe adverse effects on the immune system. While they are related, these terms refer to different mechanisms and outcomes. This text explores the distinctions...
Drug Attrition Due to Immune-Mediated Risk

Drug Attrition Due to Immune-Mediated Risk

by | Jun 20, 2024 | Blog

Drug attrition, or the failure of drug candidates during development, remains a significant challenge in pharmaceutical research. One of the critical factors contributing to this high attrition rate is immune-mediated risk, where the immune system reacts adversely to...

Immune Modelling & Experimental Design

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Immune Risk Assessment

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Tissue Damage & Cytotoxicity

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Immuno-Oncology & Immunotoxicity

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Inflammation & Systemic Diseases

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Vaccines, Drug Delivery & Transfection

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Signalling Pathways

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Looking for a tailored solution?

Of course, there is no one-size-fits-all solution for most studies. Immundnz specializes in developing tailored assays to enable you to challenge the status quo in your research.

 

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Some of our popular assays

To accelerate your research and deliver high-quality data, Immundnz offers a broad spectrum of standardized, proven assays that are readily available.
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M1/M2 Polarisation

M1/M2 are important in studies of various therapeutic areas and biological pathways.

 

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ADCP

Phagocytosis is an immunologic mechanism involved in apoptosis, necrosis, infection and tumour conditions mediated by leukocytes like macrophages, DCs, and neutrophils. 

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Cytokine Release Assay

Cytokine release assay (CRA) is vital in biopharmaceutical discovery and development and life science research.

 

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Dendritic Cell Maturation

Dendritic cells (DCs) are the star antigen-presenting cells (APCs) of myeloid or haematopoietic origin that play a vital role between the innate and adaptive immune systems. 

 

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T Cell Differentiation

The T cell proliferation assay can be used to assess modulation of the T cell response by (immunomodulatory) compounds.

 

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Immune & Protein-Based

We perform various immunologic and protein-based assays that are needed in your research or drug development.

 

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Case Studies

Immundnz has performed many case studies, some of which are described here. You can always reach out to us for other examples of projects we have done.

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Blogs

Immundnz shares insights on in vitro immunology research for drug discovery on its blog, which is regularly updated by experts in the field.

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