ADCP Assays in Drug Discovery

ADCP Assays in Drug Discovery

by | Jun 7, 2024 | Blog

Antibody-dependent cellular phagocytosis (ADCP) is a vital immune mechanism that involves the engulfment and digestion of antibody-coated cells by phagocytes such as macrophages, monocytes, and dendritic cells. This process is crucial for clearing pathogens and...
ADCC Assays in Drug Discovery

ADCC Assays in Drug Discovery

by | May 27, 2024 | Blog

Antibody-dependent cellular cytotoxicity (ADCC) is a pivotal immune mechanism whereby effector cells, such as natural killer (NK) cells, recognize and lyse target cells that are opsonized with antibodies. This process is integral to the function of many therapeutic...
Tissue Damage Assays in Drug Discovery

Tissue Damage Assays in Drug Discovery

by | May 21, 2024 | Blog

Tissue damage assays play a crucial role in drug discovery and development by enabling researchers to assess the effects of potential therapeutic agents on tissue integrity, repair mechanisms, and pathological processes. These assays provide valuable insights into the...
NK Cell Assays in Drug Discovery

NK Cell Assays in Drug Discovery

by | May 13, 2024 | Blog

Natural killer (NK) cells are innate immune cells with potent cytotoxic activity against infected and malignant cells, as well as regulatory functions in immune responses. NK cells play a crucial role in host defense against pathogens and surveillance against tumors....

Immune Modelling & Experimental Design

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Immune Risk Assessment

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Tissue Damage & Cytotoxicity

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Immuno-Oncology & Immunotoxicity

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Inflammation & Systemic Diseases

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Vaccines, Drug Delivery & Transfection

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Signalling Pathways

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Looking for a tailored solution?

Of course, there is no one-size-fits-all solution for most studies. Immundnz specializes in developing tailored assays to enable you to challenge the status quo in your research.

 

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Some of our popular assays

To accelerate your research and deliver high-quality data, Immundnz offers a broad spectrum of standardized, proven assays that are readily available.
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M1/M2 Polarisation

M1/M2 are important in studies of various therapeutic areas and biological pathways.

 

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ADCP

Phagocytosis is an immunologic mechanism involved in apoptosis, necrosis, infection and tumour conditions mediated by leukocytes like macrophages, DCs, and neutrophils. 

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Cytokine Release Assay

Cytokine release assay (CRA) is vital in biopharmaceutical discovery and development and life science research.

 

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Dendritic Cell Maturation

Dendritic cells (DCs) are the star antigen-presenting cells (APCs) of myeloid or haematopoietic origin that play a vital role between the innate and adaptive immune systems. 

 

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T Cell Differentiation

The T cell proliferation assay can be used to assess modulation of the T cell response by (immunomodulatory) compounds.

 

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Immune & Protein-Based

We perform various immunologic and protein-based assays that are needed in your research or drug development.

 

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Case Studies

Immundnz has performed many case studies, some of which are described here. You can always reach out to us for other examples of projects we have done.

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Blogs

Immundnz shares insights on in vitro immunology research for drug discovery on its blog, which is regularly updated by experts in the field.

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