ADCC Assays in Drug Discovery
Antibody-dependent cellular cytotoxicity (ADCC) is a pivotal immune mechanism whereby effector cells, such as natural killer (NK) cells, recognize and lyse target cells that are opsonized with antibodies. This process is integral to the function of many therapeutic...
Tissue Damage Assays in Drug Discovery
Tissue damage assays play a crucial role in drug discovery and development by enabling researchers to assess the effects of potential therapeutic agents on tissue integrity, repair mechanisms, and pathological processes. These assays provide valuable insights into the...
NK Cell Assays in Drug Discovery
Natural killer (NK) cells are innate immune cells with potent cytotoxic activity against infected and malignant cells, as well as regulatory functions in immune responses. NK cells play a crucial role in host defense against pathogens and surveillance against tumors....
T Cell Assays in Drug Discovery
T cells are central players in the adaptive immune system, orchestrating immune responses against pathogens, tumors, and other threats. Their ability to recognize specific antigens and coordinate diverse effector functions makes them attractive targets for therapeutic...
