Signalling pathways transform extracellular signals into cellular effects on transcription factor-mediated gene regulation. Extracellular information sensed at a cell’s surface must be converted into an intracellular response using a complicated network of interconnected signaling cascades. Cellular responses like proliferation, differentiation, secretion, and death are all regulated by these signaling events and thus essential aspects to investigate.
Map the key interactions that control cell activity and function and influence drug efficacy.
Kinase and other signaling enzyme activity assays are essential tools for researchers researching a broad range of signaling events. They are also commonly utilized in drug development applications to evaluate drug:target interactions. Immundnz helps to provide specific testable hypotheses to guide functional studies to identify critical regulators involved in drug development.
Learn how Immundnz guides Signalling Pathway Research
In this case study, we test the effect of a modified macrophage medium in inducing the differentiation of anti-tumour macrophages in cancer therapy.
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